Held goalless by Peru, the Paris Saint-Germain forward and his nation went out of the Copa America in a shoot-out in Salvador.
Cavani played the whole game and tucked away his spot-kick in the shoot-out, but could not add to his tally of two goals in the competition as Uruguay missed out on a place in the last four.
URUGUAY - PERU: 0-0 (4-5 on pens.)
Copa America - Quarter-final
Arena Fonte Nova (Salvador de Bahia)